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Seretide Diskus 50+500 mcg

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What is Seretide Diskus

Seretide inhalers are used to treat and prevent Asthma (wheezing and shortness of breath) and Chronic Obstructive Pulmonary Disorders (COPD)

Seretide Diskus 50/500 contains two salts: Salmeterol(50mcg)+ Fluticasone Propionate (500mcg), effectively treating Asthma and COPD.

Your physician will prescribe Seretide dosage and instruct you on how often to use it. 

Uses of Seretide Diskus

Seretide Diskus 500 mcg helps treat and prevent Asthma attacks and Chronic Obstructive Pulmonary Disorders (COPD). 

Seretide lets you engage in more physical activity without experiencing wheezing, coughing, or shortness of breath.


Asthma is a chronic respiratory disorder in which the airways narrow, swell, and generate excess mucus, resulting in breathing problems. 

It can make breathing difficult and cause coughing, wheezing (a whistling sound when exhaling), and shortness of breath.

Chronic Obstructive Pulmonary Disorder (COPD)

COPD is a category of lung illnesses that leads to airflow obstruction in the lungs, which makes it hard to get the air out of the lungs. 

Owing to this obstruction, individuals have difficulty breathing or become exhausted due to the strain of breathing.

How does Seretide Diskus work

Seretide diskus 50/500 is a combination of two salts, Salmeterol and Fluticasone Propionate. 

Salmeterol is a long-acting bronchodilator that relaxes the airway muscles and enlarges the airways. Thus, it facilitates breathing.

Fluticasone Propionate belongs to the class of corticosteroids that work by acting on the inner cells of the nasal lining. It prevents the release of inflammatory-causing chemicals. 

Therefore, it alleviates sneezing, a runny or plugged nose, and sinus pain. 

Together they work to control the symptoms of Asthma and Chronic Obstructive Pulmonary Disorders (COPD). 

How to use Seretide inhalers

Seretide Diskus 500 mcg is for inhalation purposes only. You must use the inhaler properly to get the most out of this medicine. If you don't, it will not function as it claims.

Take Seretide Diskus 50/500 mcg by inhaling the number of puffs recommended by your doctor. 

Your physician will determine the frequency of Seretide dosage based on your medical condition.

Usually, Seretide inhalers are used daily for maximum benefit, even when asymptomatic. 

Do not use it to treat Asthma attacks that occur suddenly. Use your quick-relief inhaler (reliever) if you experience an Asthma attack.


A Seretide inhaler is available in one more variant other than 50 mcg + 500mcg

Side effects of Seretide Diskus 

Take your medication as your doctor prescribes. Side effects are temporary and very less likely to occur. Consult your doctor if the symptoms persist or cause you 

Common side effects of Seretide

  • Vomiting 
  • Fungal infection of the mouth
  • Hoarseness of voice
  • Musculoskeletal (bone, muscle, or joint) pain
  • Nausea
  • Increased heart rate
  • Cough
  • Respiratory tract infection
  • Headache
  • Sore throat

These side effects are uncommon, and only a small number of people experience them. The majority of adverse effects are not severe.

Interactions of Seretide Diskus 

Seretide may occasionally interact with specific drugs and diseases. It might have unexpected adverse effects. Be sure to discuss interactions with your doctor.

Drug Interaction

Learn about drug-drug interactions to identify which medicine pairings patients should avoid.

Drug interactions of Seretide 

  • HIV medicines (Atazanavir)
  • Fluid retention drugs (Furosemide)
  • Corticosteroids (Budesonide)
  • Bronchodilators (Vilanterol, Formoterol)
  • Blood pressure medicines (Metoprolol)
  • Respiratory drugs (Ipratropium)
  • Medications to induce labor (Oxytocin)

Disease Interaction

In drug-disease interactions, the medication used to treat one disease worsens the state of a patient suffering from another illness.

Disease interactions of Seretide

  • Hyperadrenocorticism
  • Cataracts
  • Diabetes
  • Liver Disease
  • Fungal infection
  • Bacterial infection
  • Viral infection
  • Cardiovascular diseases 
  • Kidney disease
  • Glaucoma

Food Interaction

A drug-food interaction happens when a person's food and medication interact negatively.

Seretide Diskus interacts negatively with grapefruit or grapefruit juice. Therefore, grapefruit and grapefruit juice should be avoided when using Seretide 50/500 inhalers because they may cause significant side effects.

Precautions for using Seretide Diskus  

Before using, determine the following precautions:

  • The Seretide inhaler is not used to treat acute Asthma symptoms or sudden Asthma attacks requiring fast and short-acting inhalers
  • Inform your doctor if you are pregnant or breastfeeding before using Seretide 50 mcg/500mcg Accuhaler
  • It is not for children below 12 years of age
  • Before taking this medication, you should contact your doctor if you have kidney, liver, diabetes problems, chest infections, Glaucoma, etc., so that he or she can prescribe the correct dosage
  • If the salt component of this inhaler has caused you to experience side effects in the past, do not use it. Instead, consider switching to an inhaler with a different salt component.


Place in a cool, dry place away from direct sunlight. Also, keep it out of children's reach. 

Frequently Asked Questions (FAQs)

Why is Seretide Diskus 500 mcg+50 mcg not used for acute Asthma?

Seretide Accuhaler should not be used to treat acute Asthma symptoms that require a fast-acting bronchodilator. Seretide contains Salmeterol, which is a long-acting bronchodilator. 

Is Seretide Accuhaler a preventer or reliever?

Seretide is typically referred to as a 'preventer' or 'controller' inhaler because it helps to prevent Asthma and COPD symptoms such as shortness of breath. Additionally, it can reduce the likelihood of an Asthma attack.

What happens if you take too much Seretide?

You may rarely overdose if you use Seretide according to your doctor's instructions. Still, if you take too many puffs, you may experience adverse effects such as dizziness, shaking, or a fast heartbeat. If you have taken too many puffs and are concerned, consult your doctor.

Does Seretide 50/500 mcg make you put on weight?

NO. The Seretide inhaler contains such a small amount of steroids that you will not gain weight while using it.

What happens if I stop taking Seretide?

Do not suddenly discontinue or reduce your Seretide dosage. It could make breathing more difficult. Additionally, if you suddenly stop taking Seretide or decrease your dose, this may (very rarely) result in difficulties with your adrenal gland, leading to side effects.

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