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Penegra 100 Mg

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Medically Reviewed by
Dr. Akanksha Kaushal
akanksha-kaushal Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRx Medicine, ensuring accurate pharmaceutical information is accessible to all.

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Written by
Julian Carter
julian-carter Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at Goodrxmedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

About Penegra 100 mg

The active component in Penegra 100 is called Sildenafil Citrate.

Impotence, commonly known as Erectile Dysfunction, can be treated with this medicine.

The inability of a man to obtain and maintain his erection is considered impotence.

Because it enhances blood circulation in the penis, this medicine makes it easier for a man to acquire an erection in response to sexual stimulation.

Zydus Lifesciences is a manufacturer of Penegra pills.


Penegra is a medicine that is recommended for individuals with Erectile Dysfunction.

The inability to attain or keep an erection firm is one of the symptoms of impotence.

Boosting the amount of blood that flows to a man's penile region makes it easier for him to maintain a firm erection.

Other medicines containing Sildenafil can treat Pulmonary Arterial Hypertension.

How it works

These Sildenafil tablets inhibit the Phosphodiesterase Type 5 (PDE5) activity.

By inhibiting PDE5, one can stimulate the formation of Cyclic Guanosine Monophosphate (cGMP), which helps relax the penile smooth muscle.

By relaxing these smooth muscles, blood flow to the male genitalia increases, leading to a firm erection.

Also, remember that sexual stimulation is necessary to have an erection.


You should take this medication exactly as prescribed by your doctor.

If more than one tablet is taken regularly, overdosing is possible.

The Penegra 100 mg Sildenafil tablet should be swallowed with a full glass of water; it should not be broken, chewed, or crushed first.

This medication is best taken between 30 and 60 minutes before you want to engage in sexual activity.

Alternatives to Penegra include Cenforce and Fildena, both of which include Sildenafil as their active ingredient.

Side effects of Sildenafil Penegra

Possible side effects of this Sildenafil 100 mg tablet include the following, ranging from common to rare:

  • Flushing
  • Headache
  • Sneezing
  • Difficulty in sleeping
  • Pain in the eyes
  • Painful urination
  • Pain in the muscles
  • Bleeding nose
  • Diarrhea
  • Burning or tingling sensation in the skin


There is a possibility that Sildenafil will have an adverse effect when used with other medications, conditions, or foods.

Drug interactions

The likelihood of experiencing adverse effects from a combination of medications is higher. Consequently, it would be best if you avoided the following:

  • Nitrate medication
  • Riociguat
  • Prostate disorder and high blood pressure medications
  • HIV/AIDS medications
  • Antifungal and antibiotic medicines
  • Any other ED or PAH treating pills

Disease interactions

Before taking this Sildenafil tablet, discussing your medical history with your doctor is essential. If you have any of the following health conditions, you should not take Penegra tablets:

  • Cardiovascular diseases or disorders
  • Low or high blood pressure
  • Stomach ulcer
  • Liver and kidney diseases
  • Blood cell disorders like Leukemia, Sickle Cell Anemia, and Multiple Myeloma
  • Pulmonary Veno-Occlusive disease
  • Retinitis Pigmentosa
  • Peyronie's disease (penis deformation due to scar tissue)

Food interactions

While using this medication, you should not consume grapefruit juice or alcohol.

Consuming a high-fat diet while using Sildenafil 100 mg can lessen the medication's effectiveness.


It is vital to keep the following in mind before and after using this medication:

  • For those who have experienced an adverse reaction to Sildenafil Citrate in the past, this medication is not recommended
  • Males under the age of 18 should not take this medication
  • Consumption of Penegra by women is not recommended
  • After consulting with a physician, they can take Lovegra, the female equivalent of Viagra
  • Consuming alcoholic beverages while under the influence of this medicine could result in severe adverse effects
  • If you suffer any unwanted symptoms while taking this medication, including blurred vision or dizziness, you should immediately stop


The optimal storage conditions for Penegra 100 mg are below 30 degrees Celsius in a dark, cool environment.

Frequently Asked Questions

Is Penegra a prescription drug?

Penegra tablets are a prescription treatment for Erectile Dysfunction (ED) that should only be taken as per the directions provided by your medical professional.

What is Penegra 100 used for?

Penegra 100 is frequently prescribed to men with impotence, also known as Erectile Dysfunction.

Sildenafil Citrate, the active ingredient in this medication, dilates blood vessels in the male genital organ, increasing blood circulation. Consequently, a man can attain and maintain an erection.

How long does Sildenafil last?

The effects of Sildenafil could last for up to four hours. On the other hand, the medicine will continue to be present in your system for 24 hours.

How long does it take for Sildenafil 100 to work?

It takes between 30 and 60 minutes for a 100 mg dose of Sildenafil to become effective. However, it also depends on the health status of the individual.

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