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Tadalafil Side Effects and How to Avoid Them

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Written by- Julian Carter

Tadalafil is a popular medicine well-known for treating Erectile Dysfunction (ED). It is available in pharmacies under the brand name Cialis. 

It is a Phosphodiesterase-5 (PDE5) inhibitor that dilates the blood vessels and improves penile blood flow.

As Tadalafil (or Cialis) affects the body’s blood circulation, it can produce side effects. 

This article aims to understand the common and uncommon Tadalafil side effects. It also covers Tadalafil warnings and precautions to ensure safe usage. 

Side effects of Tadalafil

As with any medication, Tadalafil, used to treat ED, may induce side effects in some patients. These side effects are usually mild, like headaches, dizziness, and nasal congestion. 

The mild side effects are common and resolve within a few hours. But in certain rare circumstances, the medicine can cause serious side effects.

Common Tadalafil side effects

The common Tadalafil side effects are mild and temporary. The commonly reported adverse reactions include:

  • Patients often report experiencing mild to moderate headaches after taking Tadalafil
  • Due to increased blood flow, some individuals may experience facial flushing or redness in the face
  • Tadalafil may occasionally induce indigestion or stomach discomfort
  • Muscle pain or discomfort, typically felt in the back, is a possible side effect 

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Did you know?
The U.K National Health Service reports that 1 in 100 people experience common side effects from Tadalafil. Meanwhile, 1 in 1000 people experience its rare side effects.

Severe Tadalafil side effects

Although uncommon, Tadalafil may have severe side effects requiring immediate medical attention. 

Stop taking Tadalafil and call a doctor if you experience the following symptoms. 

Vision or hearing loss

Hearing lossSource: Motortion_from_Getty_Image
Hearing loss

Reports suggest that Tadalafil can cause changes in vision or hearing. Temporary visual and auditory changes are normal with Tadalafil use and are not a cause for concern.

But the medicine has also been linked to rare hearing or vision loss reports. Seek immediate help if you experience hearing or visual changes after taking Tadalafil.


Priapism is a rare side effect of Tadalafil, producing a painful erection lasting several hours. 

Although uncommon, Priapism is a severe side effect. It requires immediate medical intervention to prevent long-term complications.

Allergic reactions

Some people may experience allergic reactions to Tadalafil. The symptoms include rashes, itching, puffiness, and difficulty breathing. 

Get medical attention if you notice symptoms of an allergic reaction.

Chest pain or heart conditions

Tadalafil may pose a risk to patients with underlying heart conditions. It may cause chest pain, heart palpitations, or other symptoms in people with heart disease.

Seek immediate medical help if you encounter any of these symptoms. Your doctor may recommend a lower dose of Tadalafil or prescribe an alternative Erectile Dysfunction pill.

These side effects are uncommon and may occur due to an overdose. Immediately seek medical attention if you take more than one dose of Tadalafil.

Tadalafil warnings

Tadalafil may be unsafe for all patients and may interact with certain medicines or medical conditions.

Before taking Tadalafil, individuals with kidney or liver disease should consult a healthcare professional. You must take caution if you have a history of strokes or heart attacks. 

Tadalafil can interact with Nitrates, which helps treat Angina (chest pain). The two medicines, when combined, can cause a dangerous decline in blood pressure.

Patients need to inform their doctors of their medications to avoid potential Tadalafil interactions.

You should not use Tadalafil recreationally or in combination with illegal drugs. This practice can result in severe health complications.

In addition, avoid excessive consumption of alcohol when taking Tadalafil, as it may worse the side effects.

Tips for the safe use of Tadalafil

Tadalafil may be safe if you follow your doctor’s instructions when taking the medicine. Ensure you take the medication as prescribed and inform your doctor of any unusual side effects. 

Additionally, it is vital to avoid any drugs, foods, or beverages that interact with the medication. 

Take Tadalafil as prescribed

Take Tadalafil as prescribed by your doctor. Do not increase the recommended Tadalafil dosage or change the dosing schedule without medical supervision.

Avoid consuming alcohol or grapefruit juice

Avoid alcoholSource: Africa_Image
Addicted to alcohol

Alcohol and grapefruit juice can interact with Tadalafil and increase the risk of adverse reactions. Doctors recommend limiting or avoiding their consumption during Tadalafil therapy.

Excessive alcohol consumption before taking Tadalafil can enhance the blood pressure-lowering effect of the medicine.

Report unusual side effects

If you experience any severe or unusual adverse effects while taking Tadalafil, contact your healthcare provider immediately for evaluation and guidance.

Tadalafil side effects — the bottom line

Tadalafil is an effective treatment for both Erectile Dysfunction and Pulmonary Arterial Hypertension. But you should be aware of the potential Tadalafil side effects. 

The common side effects are mild and temporary and go away when the medicine wears out of the body. If you take Tadalafil as prescribed, you will experience fewer side effects.

The severe side effects of Tadalafil are rare but require immediate medical attention. They usually occur due to an overdose, an allergic reaction, or a harmful drug interaction.

Discussing your health history and medications with your doctor before taking Tadalafil will help you avoid adverse reactions. 

Always seek the advice and recommendations of a healthcare professional before using Tadalafil.

Frequently Asked Questions

What are the dangers of Tadalafil? 

The risks of Tadalafil include allergic reactions, cardiovascular risks, Priapism, and uncommon vision or hearing changes. 
You must seek medical attention immediately if you experience severe side effects.

What happens if you take Tadalafil every day? 

You can take Tadalafil (Cialis) daily to manage ED or BPH symptoms. Your physician may prescribe a low dose for daily use.
Follow dosage instructions and consult a healthcare professional for personalized advice. You must only take Tadalafil daily under medical supervision due to the increased risk of side effects.

Can Tadalafil damage your heart?

Tadalafil can negatively impact the heart in patients with cardiovascular disease. It has the potential to decrease blood pressure
Consult a healthcare provider before taking Tadalafil if you have heart-related issues, such as a recent heart attack, stroke, or other cardiovascular issues. 
Discuss heart conditions and medications before using Tadalafil.

Who should avoid Tadalafil?

People who take certain medicines or have specific medical conditions should avoid Tadalafil. 
People who take nitrates should not take Tadalafil as they may experience a negative interaction. 
Avoid taking Tadalafil if you have heart disease or severe kidney or liver disease. 

Does Tadalafil have long-term side effects?

Tadalafil’s long-term side effects are not well-documented. Tadalafil may be safe for long-term use when used as prescribed. Side effects usually go away with time or dosage changes. 
Monitor your vision, hearing, and cardiovascular health during long-term Tadalafil use. Report any concerns to a healthcare professional immediately. 

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