We’d Love To help

Reach out to us we will get back to you

Preferable Time to Call


Levitra and Tadalafil: Understanding the Differences

Gina Walters


levitra vs tadalafil

When treating Erectile Dysfunction (ED), several effective medications are available to help men regain their sexual confidence and performance.

Levitra and Tadalafil are two widely prescribed medications. 

While they belong to the same group of medications known as Phosphodiesterase type 5 (PDE5) inhibitors, they have distinct properties and benefits. 

This article will compare Levitra and Tadalafil, highlighting the differences between the two medicines so that you can make an informed decision.

About Levitra and Tadalafil

Levitra is an oral Erectile Dysfunction pill, usually recognized by its generic name Vardenafil. 

It works by suppressing the PDE5 enzyme, allowing the smooth muscles of the penile area to relax. 

This relaxation increases blood flow to the penis, making it easier to establish and maintain a hard erection during sexual stimulation. 

Tadalafil, known by its brand name Cialis, is a common Erectile Dysfunction medicine in the PDE5 inhibitor class. 

Tadalafil, like Levitra, works by relaxing the penile muscles, thus increasing blood flow to the penile area, thereby promoting erections.

Both Tadalafil and Vardenafil work similarly, but they differ in onset and duration of action.

Duration of action

a banana leaking to simulate ejaculatingSource: atlasstudios
Tadalafil is also called the weekend pill

The onset and duration of action of Levitra and Tadalafil is the key difference between the two. 

Levitra usually starts working within 30 to 60 minutes of taking it. Tadalafil takes longer, usually 1 to 2 hours before its effects become visible. 

Often referred to as the “weekend pill,” Tadalafil can last up to an impressive 36 hours.

Whereas Levitra’s effects can last up to 4-5 hours making it a better choice for spontaneous sexual activity.

This distinction may be important for people who want immediate results versus others who want more flexibility in their sexual relationships. 

Tadalafil’s longer duration of action allows for a more relaxed approach to intimacy without the necessity to schedule sexual activities in a short timeframe.

Wondering how much time it takes for Cialis’ effects to wear off? Read now: Know How long does Cialis stay in your system?


Both Levitra and Tadalafil are quite popular when it comes to treating Erectile Dysfunction

The starting dosage of Vardenafil (Levitra) is commonly 10 mg, but it can be adjusted to 5mg or 20mg, depending on the response to the medicine. 

Tadalafil, on the other hand, offers lower continuous daily doses of 2.5mg and 5mg, as well as larger as-needed doses of 10mg and 20mg. 

Since multiple dosages of Tadalafil and Vardenafil are available, doctors can personalize treatment strategies per individual needs.


It is critical to evaluate potential interactions and precautions before starting any medicine. 

Certain medicines, such as Nitrates used to treat chest discomfort, and alpha-blockers used to treat prostate problems or Hypertension, may interact with Tadalafil and Levitra.

To avoid potentially hazardous interactions, patients should reveal their medical history and all current medications to their doctors.

Consult a doctor before taking any of the two medicines. Your doctor can recommend the right dosage and avoid the chances of any interaction.

Side effects

A man suffering from headacheSource: SIphotography
Headache is a minor side effect of consuming ED Medication

Like all medications, Levitra and Tadalafil may have potential side effects

Headaches, indigestion, stuffy or runny nose, and flushing are common side effects of both medicines.

Some Levitra users may also experience rare visual disturbances.  

But Tadalafil users are less likely to experience such problems because of its longer half-life.

If any concerning side effects occur and persist, it is essential to seek medical advice.

Learn about the side effects of Levitra to make informed choices. Read: Understanding Vardenafil Side Effects, Interactions, Precautions: All You Need To Know

Cost Considerations

Cost is a significant factor for many patients when choosing between Levitra and Tadalafil.

Tadalafil’s longer duration of action may cut costs over time because of its longer duration of action. 

On the other hand, some people might find the price of Vardenafil more economical.

Generic nameVardenafilTadalafil in itself is the generic version of Cialis
Onset of action30-60 minutes1-2 hours
Duration of action4-5 hours36 hours
Cost considerationGeneric version might be less expensiveLonger duration may save cost over time
Quick Checkout
Unlock Your Bedroom’s Potential – Try Levitra and Take Your Sexual Performance to New Heights!


In conclusion, Levitra and Tadalafil are effective medications for treating Erectile Dysfunction. 

The key differences lie in their onset and duration of action, with Levitra offering quicker results and Tadalafil providing an extended window of opportunity for intimacy. 

Additionally, dosage options, potential interactions, side effects, and cost considerations should all be considered when deciding. 

Consulting a doctor is important to determine the most suitable choice for individual needs.

PDE inhibitors: These help in inhibiting PDE5 enzyme thus relaxing the penile muscles and increasing blood flow which helps in treating ED.

Frequently Asked Questions

How do Levitra and Tadalafil work to treat Erectile Dysfunction (ED)?

Levitra and Tadalafil belong to the PDE5 inhibitor class, which helps relax the muscles in the penile region, thus increasing blood flow. This improved blood circulation aids in achieving and maintaining an erection during sexual stimulation.

What are the main differences between Levitra and Tadalafil regarding onset and duration of action?

Levitra usually starts working within 30 to 60 minutes after consumption, while Tadalafil has a slower onset, taking around 1 to 2 hours to become effective. Regarding duration, Levitra’s effects last for approximately 4 to 5 hours, whereas Tadalafil’s effects can last up to an impressive 36 hours, earning it the nickname “weekend pill.”

Are there any dosage variations between Levitra and Tadalafil?

Yes, there are differences in dosage options for both medications.  Levitra is commonly available in 5mg, 10mg, and 20mg doses, with 10mg being the most frequently prescribed starting dose. Tadalafil offers 2.5mg and 5mg daily doses for continuous use and 10 and 20mg for as-needed dosage.

Are there any potential interactions with other medications that need to be considered when taking Levitra or Tadalafil?

Levitra and Tadalafil may interact with certain medications, particularly Nitrates for chest pain and alpha-blockers prescribed for prostate problems or Hypertension. It is crucial to inform your doctor about all your medications to avoid harmful interactions.

Do Vardenafil and Tadalafil have any notable side effects, and are they different from each other in this regard?

Both medications may have common side effects, such as headaches, indigestion, stuffy or runny nose, and flushing. Vardenafil, in particular, may cause visual disturbances in some individuals. However, Tadalafil users are less likely to experience such side effects due to its longer half-life. Consult your doctor for appropriate guidance if you experience any concerning side effects.

When referencing outside resources, GoodrxMedicine always provides full citations. To learn more about the measures we use to maintain the quality of our content, please review our Content Information Policy.

More Articles Like This