A low sex drive can affect many parts of a woman’s life, including relationships, self-esteem, and emotional well-being. When this happens for a long time, you often start searching for safe and effective drugs to increase libido in women. Low desire is not uncommon and can be caused by various factors, including hormonal imbalances, stress, medical conditions, medications, lifestyle changes, or emotional issues.
Today, women have more options than before. Doctors can prescribe approved medications to increase female libido, like Addyi or Vyleesi, or recommend treatments that support hormones, mental health, or underlying conditions. Some women may also benefit from counseling or personalized medical plans.
This article explains the medicines that are approved, how they work, who they are meant for, and what women should know before choosing any low libido treatment. The goal is to help women understand their choices clearly, safely, and confidently.
FDA-approved medicines that increase female libido
Only two medications are officially approved by the FDA to treat low libido in premenopausal women. These medicines are recommended for women who have ongoing low desire that is not caused by another medical problem, relationship issue, or medication side effect.
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Flibanserin (Addyi)
Flibanserin is a once-daily prescription tablet used to treat Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women. Unlike medicines that work immediately before sexual activity, Addyi is meant to be taken every night so it can gradually balance certain brain chemicals that influence mood and desire. Because of this, results develop slowly over several weeks, not instantly.
Doctors usually consider Addyi when a woman has had a long-lasting drop in sexual interest that stress, Depression, relationship conflicts, or another health condition cannot explain.
Women taking this medicine must avoid alcohol completely, as mixing both can lead to dizziness or a serious drop in blood pressure. When used correctly and consistently, Flibanserin can help restore healthy sexual interest and improve overall quality of life.
Bremelanotide (Vyleesi)
Bremelanotide, known by the brand name Vyleesi, is another FDA-approved option for low female libido, but it works in a completely different way than Addyi. Instead of daily dosing, Vyleesi is used only when needed. Women self-inject it under the skin about 45 minutes before intimacy, allowing the medicine to activate specific brain receptors that help enhance sexual desire.
This medication is approved only for premenopausal women diagnosed with HSDD and is preferred by those who want flexibility rather than a daily routine. While mild side effects like nausea, flushing, or redness at the injection site may occur, many women still find Vyleesi helpful because it supports sexual desire only at the moments they choose to use it.
For women who want an on-demand option rather than a long-term daily treatment, Vyleesi can be a practical and effective choice.
Other medical options
In many cases, healthcare providers recommend other medical treatments that support natural desire by correcting hormonal changes, mood-related issues, or underlying health problems.
Hormone therapy
Hormones have a powerful influence on women’s sex drive, and even small changes in levels can affect desire. During perimenopause, menopause, or after certain medical treatments, the body produces less estrogen or testosterone, leading to dryness, discomfort, and reduced interest in intimacy.
In such situations, estrogen therapy can improve vaginal moisture, ease discomfort, and help women feel more physically comfortable during sexual activity. Some women also benefit from carefully monitored testosterone therapy, especially when tests show low levels of this hormone.
Because hormonal treatments must match each woman’s health needs and may cause side effects, doctors always supervise their use to ensure safe and appropriate dosing.
Off-label medications
Certain drugs to increase female libido are not officially approved by the FDA. Yet, some doctors may prescribe them when low desire appears related to mood changes, anxiety, or brain-chemistry imbalances. These options are considered off-label, meaning they are used based on a clinician’s judgment and not FDA-approved for boosting sexual desire.
Bupropion (Wellbutrin) is an antidepressant that has shown potential and is prescribed to help manage HSDD in women. It works by influencing serotonin, dopamine, and norepinephrine, similar to Addyi, but it is not FDA-approved for treating low libido.
Because these medicines directly affect brain chemicals, the risks can be significant. Professional guidance is essential; self-medicating or using them without supervision can worsen mood, cause side effects, or create new health issues.
Always consult a healthcare provider before considering any off-label treatment for sexual health, especially those that modify mood or neurotransmitters.
Treating underlying health conditions
For many women, low libido is not a standalone problem but a symptom of something else happening in the body. Treating the root cause often improves sexual desire naturally, without the need for direct libido medications.
This includes managing common issues such as:
- Thyroid disorders
- Anxiety and Depression
- Chronic fatigue or pain
- Hormonal shifts
- Side effects of certain medications
Once the underlying condition is identified and treated, many women notice a steady improvement in their sexual interest and response. This approach focuses on overall well-being, which often leads to healthier and more consistent desires.
When to consult a doctor
Speaking to a healthcare professional is important when low sexual desire becomes persistent or begins interfering with daily life or relationships. A woman should seek medical guidance if she notices:
- A significant drop in libido lasting several months
- A sudden loss of interest without an obvious reason
- Pain, dryness, or physical discomfort during intimacy
- Stress, tiredness, or medication changes affecting desire
- Relationship concerns that impact sexual wellness
A doctor can help determine whether the issue is hormonal, emotional, medical, or related to another health condition. Getting the correct diagnosis ensures the treatment plan is safer, more personalized, and more effective.
Conclusion
Women experiencing ongoing low sexual desire now have several safe and effective choices. From FDA-approved medications like Addyi and Vyleesi to hormone therapy and other drugs to increase libido in women, there are multiple options available. The best approach is one guided by a trusted healthcare provider who can identify the cause and recommend the most suitable treatment.
If you are exploring drugs to increase female libido or seeking a reliable low libido treatment, professional support can help you restore confidence, comfort, and sexual well-being. Sexual health is an essential part of overall wellness, and the right guidance can make a meaningful difference.
Frequently Asked Questions
How to increase female libido instantly?
There is no guaranteed way to increase libido instantly. However, reducing stress, getting enough rest, and engaging in relaxing activities like deep breathing or a warm shower can help some women feel more comfortable and more in the mood. If low desire is ongoing, a doctor can recommend safe medical options.
How to increase female libido after 60?
Women over 60 may experience improvements in their libido by addressing hormonal changes, staying physically active, managing stress, and treating any underlying medical conditions. Doctors may also suggest hormone therapy or FDA-approved medications for low libido, depending on individual health needs.
What is the best natural female libido enhancer?
Natural options that may support libido include ashwagandha, maca Root, Ginseng, and lifestyle changes like better sleep, exercise, and stress reduction. These remedies work differently for everyone, and evidence varies, so it’s best to talk to a healthcare provider before using them.
What drink increases women’s libido?
Staying hydrated helps overall energy and mood, but specific drinks like pomegranate juice, red wine (in moderation), and smoothies rich in antioxidants may support blood flow and relaxation. These are not instant libido boosters but can contribute to better overall wellness.
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