A Ret Gel 0.1% (20 gm)

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRx Medicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at Goodrxmedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

About brand name of the drug

A Ret Gel-0.1%(20gm) is the brand manufactured by Akums Drugs in India. It is a trans derivative of Vitamin A. It is used for treatment of acne and reduce wrinkles of face. The drug is available in the form of gel. The drug is effective in the treatment of acne present and also reduces the growth of new pimples. The drug is available as 0.1% and 0.25% concentration of tretinoin. The drug is available in the tube weighing 20gm

About the drug 

A Ret Gel contains tretinoin in the concentration of 0.1% as the active ingredient. It belongs to the class of retinoids. The gel is used for the treatment of acne, prevention and healing of pimples, treatment of wrinkles, rough and patchy skin. The drug is easily available at local as well as online pharmacies. The gel is available in the tube from which the desired amount of gel can be squeezed out easily as and when required. The gel is available in different concentration of Tretinoin namely 0.1% and 0.25%.

USA Brands equivalent to A Ret Gel 7.5mg

• Retin A Gel

About salt of the drug

Tretinoin a trans derivative of Vitamin A is the key ingredient of A Ret Gel. It belongs to the class of retinoids. Retinoids are known to regulate the growth of epithelial cells. Retinoids decrease the oil production in the skin and also fights the bacteria and helps reducing acne and pimples. The retinoid also works by increasing the synthesis of new collagen in the body, it stimulates new blood vessels, giving skin a rosy appearance and also helps in reduction of spots. Tretinoin also provides a protection from the harmful UV light from the sun. Using tretinoin products along with alpha hydroxy acids provide smoothing effects to the skin.   

Medical Uses of the drug

A Ret Gel 0.1% is used for the treatment of 

• Acne vulgaris – It is a common skin disease occurring at age of puberty in this due to activation sebaceous glands oil production increases and hence clogs the pore leading to acne.
• Treat and Pimples – they are also known as spots or zits. They are a part of acne. They are also likely to occur at the age of puberty but can occur at other stages of life also. Pimple is a small pustule filled with pus which develops when the sebaceous gland becomes clogged with oil or gets infected
• Wrinkles – these are the creases or folds appearing on the skin. The underlying reason for wrinkles is ageing or exposure to UV light from the sun
• Rough patches - development of rough and dark patches on the skin probably due to pollution or exposure to harmful rays from the sun

Working of a drug 

Tretinoin present in the A Ret Gel provides relief from acne, pimples, rough and patchy skin and other skin diseases. The gel exerts its action by interacting with retinoic acid (RAR) and retinoic X receptors (RXR) located in the nucleus of the cell. These receptors help in the production of procollagen and also blocks the release of inflammatory mediators. Retinoids also works by unclogging the blocked pores. They work along with other antibiotics and allow them to enter the pores and eradicate the bacteria causing acne breakout. Topically applied drug plays a role by further preventing the degradation of skin due to UV exposure.

Side effects 

The side effects associated with A Ret Gel include:

• Skin irritation
• Burning or tingling sensation on the skin
• Red spots on skin
• Peeling or blistering of skin
• Patchy appearance of skin
• Photosensitivity
• Nausea and vomiting
• Dry mucous membrane
• Fever with body pain
• Blood cell disorder
• Difficulty in breathing
• Dizziness and fainting
• Hearing loss
• Unusual bleeding or bruising

How to use 

• Clean the area where the drug is to be used with the help of a cleanser
• Remove the desired amount of gel from the tube
• Apply at the site with the of finger 
• Use the drug during bedtime or as stated by the doctor
• Hands should be washed in a proper way with soap and water before applying the gel
• Cotton balls can also be used for the purpose of application of the gel
• In case of excessive dryness use the gel along with the moisturizer
• Replace the cap of the tube carefully after use
• In case of any allergy or adverse reactions contact the dermatologist
• Prevent contact of gel with eyes, in case the gel gets into the eyes wash with a splash of cold water
• Drug is not intended for internal use

Drugs that are known to relate with this medicine

Medicines that are known to interact with A Ret Gel are:

• Tetracycline
• Benzoyl Peroxide
• Salicylic acid
• Methoxsalen 
• Medicated soaps
• Cleansers
• Cosmetics
• Resorcinol
• Salicylic acid
• Sulfur preparations
• Products with high concentration of alcohol
• Astringents
• Certain spices
• Lime 

When to avoid taking the drug

• Avoid the drug in case of allergy to the gel
• Eczema
• Sunburn
• Hypersensitivity
• Interaction with other medicine
• During pregnancy
• Use in lactating mothers
• No to use without doctor’s recommendation
• Skin cancer

Things to avoid when using the drug 

• Avoid excessive exposure to wind and cold
• Avoid frequent washing and scrubbing of face
• Use of gel on cuts and burns is to be avoided
• Do not use hard soaps on the skin
• Avoid unnecessary touching of the face
• Avoid direct contact with sunlight
• Internal use of the drug should be strictly avoided
• Use of any other drug without doctor’s consultation is to be avoided
• Keep away from heat and flame

General Information and Precautions

• Clean and dry hands thoroughly before using them for applying the gel
• Keep the gel protected from children
• In case of allergic reactions contact your Dermatologist as soon as possible
• Avoid contact of gel with the eyes, in case the gel gets into the eye wash thoroughly with a splash of cold water
• The drugs increase sensitivity to light so use sunscreen while going out in the sun
• Hats and goggles should also be used to protect the skin from the light

PRECAUTIONS

• Alcohol – There is no interaction reported between gel and alcohol, 
• Pregnancy – the pregnant woman is not recommended to use the gel as it may affect the foetus
• Driving – The patient using the gel can go for driving or any other activities as no adverse effects related to CNS depression are reported
• Organs –the gel has no adverse effects on the working of vital organs so it is safe to use
• Lactation –The gel can cause toxicity to the baby so it’s use in lactation is not recommended.

Storage

• Store at a temperature below 80F 
• Protect from moisture
• Keep out of reach of children
• Store in a cool and dry place
• Do not refrigerate
• Store away from direct sunlight 
• Properly discard the drug after expiry
• Keep protected from heat and flame
• Do not keep the gel without it’s cap

General FAQs regarding the drug

What are the major uses of A Ret Gel?

Ans. The drug is used for the treatment of skin problems like acne vulgaris, pimples, rough patches, wrinkles.

How does A Ret Gel works?

Ans. A Ret Gel works by interacting by retinoic acids and retinoic X receptors present in the nucleus of the cell. The receptors help in the production of procollagen and blocks the release of inflammatory mediators. They also unblocked the clogged pores and along with other antibiotics fight the bacteria causing acne

What are the major side effects associated with the drug?

Ans. The use of the gel may lead to

• Skin irritation
• Burning or tingling sensation on the skin
• Red spots on skin
• Peeling or blistering of skin
• Patchy appearance of skin
• Photosensitivity
• Nausea and vomiting
• Dry mucous membrane
• Fever with body pain
• Blood cell disorder
• Difficulty in breathing
• Dizziness and fainting
• Hearing loss
• Unusual bleeding or bruising

Is A Ret Gel good for treating wrinkles?

Ans. The gel has the ability to renew skin, synthesis of procollagen and refresh the skin so the gel can be effectively used for the treatment of wrinkles