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Retino A Cream 0.025% (20 gm)

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Dr. Akanksha Kaushal
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Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRx Medicine, ensuring accurate pharmaceutical information is accessible to all.

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Written by
Julian Carter
julian-carter Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at Goodrxmedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Retino A Cream 0.025% (20gm)?

Retino A 0.025% Cream is a topical treatment used to nurse acne on the face, chest, and back. 

Additionally, it helps to soften rough face skin and eliminate fine wrinkles.

The active ingredient in the drug is Tretinoin.

It is a prescription-based drug that can be easily found online and offline in all medical stores, pharmacies, and drug stores.

Use of Retino A Cream 0.025% (20gm)

The medicine has used the treatment of:


The cream is used in the treatment of acne by clearing pores and cleansing the skin.

It also helps prevent spots on the skin, thus giving you clear and glowing skin.

As your skin becomes acne-free, this medication will enhance your disposition and boost your confidence. 

Note: It should not be applied to skin affected by Eczema or sunburn.


0.025% 20 gm of Retino A cream is an effective treatment for wrinkles. 

The cream helps prevent the development of wrinkles by keeping the skin healthy.

Acute Promyelocytic Leukaemia

It inhibits the overproduction of aberrant blood cells and increases the creation of normal, mature blood and bone marrow cells. 

Therefore, Retino A 0.025% Cream 20 gm is used to cure Leukemia (a type of blood cancer).

Retino A Cream 0.025% (20 gm)

How does Retino A Cream 0.025% (Tretinoin) work?

Tretinoin cream treats fine facial wrinkles, dark patches, and rough skin produced by the sun's UV radiation. 

It works by whitening the skin and replacing older skin cells with new ones.

It also deaccelerates the rate at which the body eliminates sun-damaged skin cells. 

Tretinoin is most effective when taken in conjunction with a skincare regimen that includes sun protection. 

Hence do not forget to parallel the cream with sun protection and hydrate yourself.

However, it does not totally or permanently eliminate these skin issues or significantly improves more noticeable skin changes, such as sun-induced or age-related deep wrinkles.


Ideal usage of Retino A Cream 0.025% (20gm) is a targeted application at night for the duration as recommended by your doctor.

Depending on the problem, the treatment's dose and duration will differ.

Typically, you should cleanse and dry the affected area before applying a thin coating of this medication. 

Follow your physician's recommendations. 

Injured or damaged skin should not be treated with it, and it should not be ingested, inhaled, or sneezed on.

Your symptoms may take weeks to subside, but constant usage is the most acceptable way to get the best benefits. 

Note: After a few weeks, if you have not noticed any improvement, you should consult your doctor again.

What to do if I forgot to apply the cream?

Apply Retino-A 0.025% Cream as soon as possible if you miss a dosage. 

If it is nearly the time for your next dose, however, you should skip the missed one and resume your regular schedule.

Do not increase the dosage.


The cream is also offered in several strengths.

Ideally, the doctor provides the dosage and therapy type based on the patient's health and age.

Retino A Cream 0.05% is a stronger concentration of the medication ( 20gm).

Side effects of 20gm Retino A Cream 0.025% 

The cream is generally safe to use.

If used as prescribed, it eliminates the possibility of unwanted side effects.

Nevertheless, a few patients may experience the following:

  • Rash
  • Hives
  • Itching
  • Fever
  • Wheezing
  • Stinging and peeling
  • Change in color of skin
  • Red and blistered skin
  • Swollen Skin
  • Swelling of face, mouth, lips, tongue, or throat
  • Intense skin irritation
  • Trouble in breathing
  • Unusual hoarseness
  • Dry skin and itching

Interactions of 20gm Retino A Cream 0.025% (Tretinoin)

Typically, normal chemicals interact with one another.

Medications can also interact and have adverse effects.

To minimise such side effects, it is best to be transparent with your doctor about your medical history and any medications you are presently taking.

Drug interactions 

The cream may interact with the following drugs:

  • Antipsychotics (Phenothiazines)
  • Immunosuppressant (Ciclosporin)
  • Anti-epileptic drug (Pentobarbital, Phenobarbital)
  • Antifungal (Ketoconazole)
  • Water pills (Thiazides)
  • Antibiotics (Erythromycin, Rifampicin, Tetracyclines, Fluoroquinolones, Sulfonamides)
  • Heart-related medicines (Diltiazem, Verapamil)
  • Medications to reduce bleeding (Aprotinin, Aminocaproic acid, Tranexamic acid)
  • Drugs for stomach ulcers (Cimetidine)

Food interactions

Vitamin A combined with cod liver oil or halibut fish oil may occasionally increase the risk of vitamin A poisoning.

Disease interactions

Before using Retino A 0.025% Cream 20 g, see your doctor if you have Eczema (itchy, swollen skin) or another skin condition.


Consider the following after using 20 grams of Retino A cream 0.025% :

  • Keep away from UV rays and exposure to sunlight after applying the cream
  • Stop using the cream if the allergic reaction or the skin condition persists or increases. Consult your doctor immediately
  • Keep the cream in proper conditions to avoid damage


Store the cream in a dry and cool place.

Please keep it away from sunlight and the reach of children.

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