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About brand name of the drug
Tadarise 5 mg is the brand produced by Sunrise Remedies in India. It is also known by the name of Cialis. The drug is used for sexual problems in men such as erectile dysfunction. It is a condition in which male does not get erection during sexual stimulation and ultimately he gets dissatisfied from his sexual intercourse. The medicine used for treating this condition is used on an alarming rate by males of USA. The easy availability of the medicine at nearly every drug store in USA has made this product reachable to everyone.
About the drug
The active pharmaceutical ingredient responsible for the action of drug in the body is tadalafil. Tadalafil works by dilating the blood vessels and increasing the blood flow in penis. Increased blood flow maintains the erection during sexual arousal. Tadarise is available in variable dose strengths ranging from 5 mg to 60 mg. Substitutes of Tadarise 5 mg is available with the name of tadalafil in USA. It can be purchased from drug stores, local pharmacies or online pharmacies.
About salt of the drug
Tadalafil is the phosphodiesterase 5 (PDE-5) enzyme inhibitor. PDE-5 enzyme is responsible for the breakdown of cGMP in body, the one which dilates the blood vessels and increase the blood flow. It takes approximately 30 minutes to drug to show its action in the body. Tadalafil maintains the erection for 3-4 hours once the drug starts showing its effect. It shows natural erection that is penis gets erected during sexual stimulation only.
Medical Uses of the drug
Tadarise 5 mg a potent drug is used for the following medical conditions:
- Erectile dysfunction (impotence): A condition faced by males when their penis does not get hardened erection during sexual arousal
- Benign prostatic hyperplasia
- Pulmonary Arterial Hypertension (PAH): A condition faced by males and females in which pressure develops in the arteries which connects the heart to the lungs. Increased blood flow after intake of medicine lower down the high pressure. Dilation of arteries increase the space which results in increased blood flow
The drug is used for shorter duration in impotence and for longer duration in PAH
Working of a drug
- Tadalafil works by inhibiting a potent enzyme called phosphodiesterase-5 (PDE-5). This enzyme is responsible for prevention of breakdown of a chemical known as cyclic guanosine monophosphate (cGMP).
- During sexual arousal, blood vessels in penis release nitric oxide (NO). NO activates an another enzyme guanylate cyclase, and this enzyme increase the levels of cGMP in the penis. Increased amount of cGMP dilates the blood vessels and increase the blood flow in penis. This maintains a long lasting erection in the penis
- Hence, tadalafil works indirectly by increasing amount of cGMP in the penis.
With every medicine there are certain side effects associated which may become severe if you have not used the drug in a fair manner. Tadarise 5 mg also shows some side effects which are numerated below:
Common side effects:
- Flushing of facial skin
- Nose bleed
- Rare side effects:
- Loss of vision or discomfort in eyes
- Loss of hearing or ringing in ears
- Heavy breathing or shortness of breath
How to use
Tadarise 5 mg is a prescription drug that is can only be purchased when doctor writes it on a piece of paper called prescription. Follow the below indicated steps for the fair use of medicine:
- Take this tablet with a glass of water at least 30 minutes prior to the sex
- It can be consume with or without food. Take it at least after 20 minutes of eating food
- Take only one tablet in a day. That too when you planned for sex
- While visiting doctor, tell him about previous medication history as well as the current medicines you are consuming
- Start with a minimal dose only. Switch to higher doses when satisfactory or desired results are not achieved
- In case if you missed the dose, take the next pill when you have planned for another sexual activity
- Do not over consume the drug, it may lead to serious adverse effects
Drugs that are known to interact with this medicine
Drug interactions are met when two drugs consumed simultaneously and they show a reaction. Such drug interactions involved with the use of Tadarise 5 mg along with the following drugs are:
- Nitrates: Nitrates are used to dilate the blood vessels and increase the blood flow into the arteries. Glyceryl nitrate if consumed along with tadalafil can show synergism and it may cause severe hypotension
- Antibiotics: Erythromycin and rifampicin etc.
- Antifungals: Itraconazole or ketoconazole
- Non-selective alpha blockers: Drugs used for treating high blood pressures such as tamsulosin and drugs used for treating enlarged prostate such as prazosin
When to avoid taking the drug
- Avoid the use of tadarise 5 mg in case of following conditions:
- If one has any previous cardiovascular disease related history and doctor has advised him for not to perform any strenuous work
- Avoid it, If you are allergic to tadalafil or any of the ingredients of tadarise 5 mg
- If you have experienced from any kind of hepatic impairment or kidney problems
- If you suffer from abnormally high and low blood pressure situations
Things to avoid when using the drug
When you are consuming this medicine make sure you do not intake any of the below mentioned things
Alcohol: Use of alcohol is strictly prohibited. It interfers with the processing of drug in the body and may lead to several adverse effects
Grape fruit: Consuming grapefruit in any of the form destroy the drug molecules in the body. It is an enzyme inhibitor which may inhibit the cGMP chemicals or guanylate cyclase enzyme which can decrease the level of cGMP in the body
General Information and Precautions
- If erection lasts for more than 4 hours or causing a painful and prolonged erection, consult a nearby physician immediately
- Keep the drug away from children, though it comes in child resistant packaging
- It should be consumed by males below 18 years of age
- Alcohol: Consumption of alcohol along with this pill is not permissible as it may inhibit the metabolism of drug molecules in the body
- Pregnancy: Use of this drug in pregnant state by females can be done only under the guidance of a registered medical practitioner. Tadarise 5 mg is used for Pulmonary Arterial Hypertension (PAH) only in females
- Lactation: The drug molecules may get secreted into breast milk and that’s why its use in lactating mothers is not allowed
- Driving: Consumption of this medicine makes a person uncomfortable and may cause sleepiness. Hence, he is not advised to drive or do any machinery work
- Organs: Organs such as heart, liver and kidney are the most prominent ones which affect the processing of this drug in the body
- The tablet shoud be stored at room temperature. Do not refrigerate
- Avoid the direct fall of light on it
- Do not keep the pills in any moist place
General FAQs regarding the drug
Does the use of Tadarise 5 mg will deform the shape of penis?
Ans. No, the use of drug in deformed penis is not allowed. It does not cause any changes in the shape of organ
Does the consumption of this pill will cause a very discomfortable erection?
Ans. No, it results into a very natural erection that is penis faces erection during sexual arousal only
Can one consume this tablet along with the use of Ayurvedic medicines?
Ans. It can be used but only when you have told to your prescriber about your past as well as current medications list
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