When it comes to using Viagra to treat Erectile Dysfunction (ED), its potential interaction with several medications often raises questions about its safety. One such Viagra interaction with Lisinopril has always been a topic of discussion and concern among Viagra users.
So, can you take Lisinopril and Viagra together? While these are often considered safe to be taken together, there are certain things that you need to keep in your mind. Both these medications treat different medical conditions and may affect your blood pressure.
Therefore, learning about Lisinopril and Viagra, their mechanism of action, potential interactions, and side effects is essential for the safe use of these medicines. This article delves into the possible interactions between Viagra and Lisinopril and explores whether it is safe to take them together.
What are Lisinopril and Viagra?
Lisinopril is an Angiotensin-Converting Enzyme (ACE) Inhibitor. The medicine treats Hypertension or high blood pressure in adults and children. It is also used in people to treat Heart Failure and to improve health conditions after a Heart Attack.
The medication often comes in tablet and solution form. Your doctor prescribes you the dose of Lisinopril, depending on the severity of your condition. The medicine is usually taken at the same time every day and controls your blood pressure.
On the other hand, Viagra, also known by its generic name Sildenafil, is a well-known medicine to improve erections in men struggling with Erectile Dysfunction (ED). It is well-recognized for its fast action, within 30-60 minutes, and long-lasting effect, up to 4 hours.
The medicine is also available in its generic form, often called generic Viagra, such as Cenforce-200, Oral Jelly 100mg, and Fildena 100mg.
Can you take Lisinopril and Viagra together?
Yes, Lisinopril and other ACE inhibitors are generally safe to take with Viagra. Studies suggest that Lisinopril and Viagra are significantly less likely to cause severe adverse effects.
However, you must consult a doctor first as both medications can lower blood pressure; their combination could potentially amplify this effect.
Your doctor can evaluate your health status to ensure this combination’s safety and effectiveness.
How do Lisinopril and Viagra work?
The working mechanisms of Lisinopril and Viagra differ significantly.
Lisinopril is an antihypertensive medication that inhibits an enzyme called Angiotensin-Converting Enzyme (ACE). This inhibition helps relax and widen blood vessels, leading to a decrease in blood pressure.
On the other hand, Viagra, containing Sildenafil, is an ED pill for treating the inability of men to get and maintain a firm erection. It belongs to a class of medication called Phosphodiesterase Type-5 (PDE5) inhibitor. Viagra works by relaxing the muscles in the penile blood vessels. This improves blood flow to the penis, which helps you get and maintain an erection when you are sexually aroused.
Aspects | Lisinopril | Viagra |
Active ingredient | Lisinopril Dihydrate | Sildenafil Citrate |
Class of medicine | Angiotensin-Converting Enzyme (ACE) Inhibitor | Phosphodiesterase Type 5 (PDE5) Inhibitor |
Common uses | Treats high blood pressure | Treats Erectile Dysfunction |
Mode of action | Inhibits ACE activity | Inhibits PDE5 enzyme |
Prescribed to | Adults and children 6 years of age | Adults above 18 years |
Possible interactions between Lisinopril and Viagra

Although safe to take together, Lisinopril and Viagra can moderately interact with each other. Taking Viagra with Lisinopril may further lower blood pressure, which is primarily a mild effect rather than a significant concern.
However, you must consult a doctor if you experience side effects like dizziness, lightheadedness, or fainting while taking these medications together.
These side effects can be more common when you first start taking Lisinopril and Viagra together or if your Lisinopril dosage is increased as your body adjusts to the combined blood pressure-lowering effect. It is unlikely that there will be severe adverse reactions.
Lisinopril and Viagra precautions
While it is safe to administer Lisinopril with Viagra, it is crucial to be cautious while taking these medicines together. You should follow the precautions for the safe use of Viagra with Lisinopril:
- Do not take these medicines if you are allergic to lisinopril or Viagra
- Always inform your doctor about your medical history, such as heart, kidney, and liver diseases. Also, consult your doctor if you take medications such as PDE5 Inhibitors (Tadalafil, Vardenafil, Avanafil) or ACE inhibitors
- Combining these medicines may cause side effects, such as headaches and lightheadedness. It is advisable to avoid driving or operating machinery after taking the dose of your medicine
- Be cautious while getting up from a sitting or lying position
- Do not change the dose, stop, or resume the medicine without consulting your doctor
- Inform your doctor if you are pregnant or breastfeeding before taking them
- Avoid grapefruit and its juices, natural supplements, and alcohol with these medications
Does Lisinopril cause Erectile Dysfunction?
No, Lisinopril does cause Erectile Dysfunction. Instead, Lisinopril may improve ED symptoms and help you achieve the desired erection during sexual intercourse. The reason behind its role in improved erection is Lisinopril’s effect on dilating blood vessels.
This effect of Lisinopril improves blood circulation throughout the body, including the penis, and facilitates erection. Hence, people with ongoing ED due to high blood pressure may observe improvement in their symptoms after taking Lisinopril.
Conclusion
Lisinopril is an ACE Inhibitor that treats high blood pressure and heart problems. Viagra, on the other hand, is a PDE5 Inhibitor that treats Erectile Dysfunction. Both are common medications. While Lisinopril and Viagra can be taken together, consulting a doctor is essential for the safe use of these medicines, especially for those with pre-existing low blood pressure.
However, Lisinopril may interact with Viagra and may lead to a drop in blood pressure, which can cause dizziness or lightheadedness. Therefore, it is necessary to be cautious while taking these medicines together and reduce the risks of side effects.
Furthermore, in some cases, Lisinopril may alleviate the ED symptoms and help men achieve the desired erection during sexual intercourse. However, it may not work the same for everyone, and you should always ask your doctor before mixing these tablets.
Frequently Asked Questions
Can I take Viagra while taking Lisinopril?
Yes, you can take Viagra while taking Lisinopril for improved erections. However, it is recommended to consult your doctor and use the prescribed dose of Viagra. It reduces the risks of side effects and ensures a faster recovery.
How long does it take for Lisinopril and Viagra to show effects?
Lisinopril typically starts to lower blood pressure within a few hours of taking the first dose, with the full effect usually seen within 2 weeks. Viagra usually takes around 30-60 minutes to start working, with peak effects occurring within 1 hour.
Can I take Viagra with slightly high blood pressure?
Yes, you can take Viagra with blood pressure. This medication is unlikely to affect a person with Hypertension if they are otherwise healthy. You must consult with your doctor before taking Viagra to avoid any potential risks.
Does Lisinopril cause Erectile Dysfunction?
No, there is no research available to prove that Lisinopril causes Erectile Dysfunction. Studies state that Lisinopril causes no significant effects on sexual activity. Additionally, the FDA has not listed ED as a side effect of Lisinopril. If you experience ED while taking Lisinopril, consult your doctor for advice.
What are the potential side effects of mixing Lisinopril and Viagra?
Mixing Lisinopril and Viagra can potentially cause dizziness, lightheadedness, or fainting due to lowered blood pressure. Consult your doctor before combining these medications to manage side effects effectively.
Can you take ED meds with Lisinopril?
Yes, you can take Lisinopril or other ACE inhibitors with ED medications. Your doctor will evaluate potential drug interactions before prescribing blood pressure or erectile dysfunction medications to ensure safety.
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