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How long does Sildenafil last?

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Written by- Julian Carter

Sildenafil Citrate is the active ingredient used in pills to stimulate the proper flow of blood in the penis. This is facilitated by relaxing the muscles around the blood vessels.

Pfizer introduced Sildenafil Citrate as Viagra in 1998. It was later, in 2017, that Sildenafil came into the market as Sildenafil Generic.

It is an FDA-approved drug and is sold to treat Erectile Dysfunction (ED) in men. 

The best-selling medicines, like Cenforce, Kamagra, Eriacta, etc., for treating ED in men have Sildenafil Citrate.

Across the world, Erectile Dysfunction is a common sexual dysfunction. It is the inability to achieve and maintain an erection during sexual intercourse.

Similarly, Sildenafil Citrate is also used in medicines to treat Pulmonary Arterial Hypertension. 

Sildenafil is also referred to as “the blue pills.” 

Understanding how long Sildenafil lasts can help users plan their sexual activities and make informed decisions about its usage. 

In this article, we will explore the duration of Sildenafil’s effects, the factors influencing its course, and other related questions.

Duration of Sildenafil’s Effects

According to studies, Sildenafil’s effects can last 4 to 6 hours. 

However, note that individual experiences may vary. 

Dosage, metabolism, high-fat meal, and overall health can influence how long Sildenafil remains effective. 

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  • Some users may find that the effects last for a shorter duration, while others may experience a more extended period of action.

    Certain medications, such as Alpha-blockers, Nitrates, or alcohol, may interact with Sildenafil and affect its duration.

    Understanding how Sildenafil works

    Sildenafil, or brand name Viagra, is a medicine used to treat Erectile Dysfunction (ED) and high blood pressure.

    Nitric Oxide is released when a person is sexually excited. This starts a chain reaction that raises the cyclic Guanosine Monophosphate (cGMP) level.

    This molecule softens the smooth muscles in the penile area and widens the blood vessels. This increases blood flow, which is needed for an erection.

    But this PDE5 enzyme breaks down cGMP, causing hindrance in attaining or maintaining an erection.

    Sildenafil is a PDE5 inhibitor, which inhibits the working of the PDE5 enzyme. Thus, the body can maintain the cGMP levels.

    How to use the Sildenafil tablet?

    According to MedicalNewsToday, Sildenafil has an average half-life of approximately 4 hours. 

    Dosing, metabolism, overall health, and age can influence how long Sildenafil stays in the system. 

    Studies claim that Sildenafil achieves its peak concentration within 30-120 minutes after ingestion.

    Note that individual responses may vary.

    According to research, Sildenafil may take about 24 hours to eliminate from your body completely.

    Recommended Read: How Does Sildenafil Work to Treat Erectile Dysfunction?

    Consult a doctor to address concerns about Sildenafil’s duration in the body and potential interactions with other medications.

    Factors Affecting Sildenafil’s Duration

    Man suffering from pain due to diabetic kidney disease Source: Albina_Gavrilovic_Getty_Images
    Kidney problem

    Several factors can influence how long Sildenafil lasts in the body

    The dosage strength plays a significant role, as higher doses may provide a longer duration of action. 

    Additionally, metabolism’s shorter metabolism can affect the absorption and elimination of Sildenafil. 

    Generally, individuals with faster metabolism have shorter durations of effect.

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    Other factors impacting Sildenafil’s duration include overall health and certain medical conditions. 

    Individuals with liver or kidney problems may metabolize the drug more slowly, prolonging its effects. 

    How long does Sildenafil last before it expires

    Sildenafil, like any medication, has an expiration date that indicates the period during which it is guaranteed to maintain its potency and effectiveness. 

    The expiration date is typically printed on the packaging or label. 

    It is essential to adhere to this date and not use Sildenafil past its expiration date. 

    Using expired Sildenafil may reduce the effectiveness or potential health risks. 

    The expiration date ensures that the medication remains stable and retains its therapeutic properties. 

    It is recommended to check the packaging for the expiration date and discard any unused or expired Sildenafil to ensure your safety and optimal treatment outcomes.

    Recommended Read: How to Take Sildenafil: A Comprehensive Guide for Safe and Effective Use


    Understanding the duration of Sildenafil’s effects is essential for individuals using this medication to treat Erectile Dysfunction

    While the average duration is around 2 to 4 hours, various factors can influence how long Sildenafil remains effective in the body. 

    By considering dosage, metabolism, and overall health and following practical tips, users can maximize the duration of Sildenafil’s effects.

    Frequently Asked Questions

    How long will Sildenafil keep you hard?

    Sildenafil typically helps maintain erections for about 2 to 4 hours after ingestion. 
    The duration may vary among individuals due to Sildenafil’s dosage, metabolism, and overall health. 
    It’s important to note that Sildenafil alone does not guarantee a continuous erection, and sexual stimulation is still required for its effectiveness.

    How long does it take for Sildenafil to wear off?

    Sildenafil typically helps maintain erections for about 2 to 4 hours after ingestion. 
    The duration may vary among individuals due to dosage, metabolism, and overall health. 
    It’s important to note that Sildenafil alone does not guarantee a continuous erection, and sexual stimulation is still required for its effectiveness.

    What is the peak time for Sildenafil?

    The peak time for Sildenafil, the active ingredient in Viagra, varies but typically occurs around 30-120 minutes after ingestion. 
    This is when Sildenafil reaches its highest concentration in the bloodstream, increasing the likelihood of achieving and sustaining an erection. 
    Individual responses may vary, so following the guidelines for optimal results is essential.

    How long does 100 mg of Sildenafil last? 

    The effects of 100 mg of Sildenafil, the maximum recommended dose for most individuals, typically last 2 to 4 hours. 
    However, it’s important to note that the duration may vary among individuals due to factors such as metabolism, overall health, and individual response to the medication.

    Sildenafil 20 mg how long does it last?

    The effects of sildenafil 20 mg typically last for about 4 to 6 hours. 

    However, the duration can vary depending on individual factors such as metabolism, overall health, and dosage. 

    It’s important to note that sexual stimulation is still required to achieve an erection during this time.

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