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Does Tadalafil Lower Blood Pressure: What You Need to Know

Gina Walters


A man getting his BP checked

Tadalafil is one of the most frequently given medications to treat Erectile Dysfunction (ED). It is the generic form of Cialis. 

Tadalafil is very effective for achieving an erection during sexual intercourse. The effects of Tadalafil can stay up to 36 hours. However, there are frequent concerns about the medicine’s effects on blood pressure. 

Tadalafil works by inhibiting the enzyme Phosphodiesterase Type 5 (PDE5) and relaxing blood arteries, which enhances blood flow.

But, does Tadalafil lower blood pressure? Yes, Tadalafil can lower blood pressure in some cases.

Before using Tadalafil, one must be aware of its side effects and interactions.

This article will explain the relationship between Tadalafil and blood pressure. 

The connection between Tadalafil and blood pressure

Tadalafil (or Cialis) is a Phosphodiesterase-5 (PDE5) inhibitor used to treat Erectile Dysfunction. PDE5 inhibitors have vasodilating effects on your body that improve the ability to get erections.

They do this by widening blood vessels, which increases blood flow. This effect can lower blood pressure in your body. 

Most patients experience a temporary decline in blood pressure . It is unlikely to have any adverse effects on your health. 

Does Tadalafil lower blood pressure

Yes, Tadalafil or Cialis may lower blood pressure due to the dilation of blood vessels. The effects of Tadalafil can stay up to 36 hours.

These effects are generally temporary and unlikely to negatively impact your health.

According to a clinical study, a healthy person does not feel any symptoms from the drop in blood pressure.  

The participants of the study experienced an average drop of 1.6 Hg in BP while lying down and 0.2 Hg in BP while standing.

Those who get a blood pressure reduction of 20 mm Hg or more may start experiencing negative effects.

Tadalafil can reduce blood pressure since PDE5 is highly concentrated in the lungs. 

It is unlikely that Tadalafil will result in a dangerously low reduction in blood pressure. 

However, certain diseases and medications may interact with Tadalafil and intensify its hypotensive effects.

Always consult your doctor before taking Tadalafil and antihypertensive drugs together. They might prescribe some other medication for managing Erectile Dysfunction Symptoms.

Effects of Tadalafil on individuals with abnormal blood pressure

When considering Tadalafil, people with Hypotension, or low blood pressure, should proceed cautiously.

Individuals with low blood pressure (BP) or any heart condition can experience greater effects after taking Tadalafil.

Tadalafil should be avoided by people taking Nitrate medications since it could further reduce their blood pressure.

It may intensify the negative consequences of Hypotension, including nausea, and impaired or dimmed vision.

Your doctor may advise you to lower your Tadalafil dosage if you use medications such as Alpha-blockers.

Many people taking Cialis wonder does Tadalafil Lower Blood PressureSource: Dontstop_Getty_Images_Signature
Tadalafil is perfectly safe for people with BP issues when prescribed by a doctor

Tadalafil interactions

It is unlikely that Tadalafil will result in a dangerously low reduction in blood pressure. 

However, some diseases and medications may make their Hypotensive effects worse.

Taking Tadalafil is not recommended for those with the following medical problems:

  • Liver problems
  • Kidney problems
  • Recent heart attack 
  • Uncontrolled Hypertension
  • Angina 
  • Uncontrolled Arrhythmia

Additionally, Tadalafil may interact with certain medications, such as:

  • Alpha-blockers
  • Nitrates (poppers)
  • Other ED pills
  • Alcohol 
  • Antihypertensives

Tadalafil can significantly lower blood pressure when combined with Nitrates, which may result in dizziness, fainting, and in rare cases, a heart attack or stroke. 

People should not take Tadalafil with low blood pressure or other medical disorders.

Consult your doctor; they can help you understand what Tadalafil is used for and who should not take it.

Recommended read: What happens when you mix Tadalafil with alcohol? Read our article to make informed choices – The Risks of Taking Tadalafil and Alcohol Together

Talk to your doctor if you use any prescribed medications or have the conditions listed above. Your doctor can assist you with adjusting your dosage.

Summing up

Tadalafil, used for treating Erectile Dysfunction, can potentially reduce blood pressure. 

To answer your question, does Tadalafil lower blood pressure? Yes, it does lower blood pressure, but the effects are mild and temporary.

However, it can further drop your blood pressure if you use high blood pressure medications like Alpha-blockers or already have a medical issue.

Talking to your doctor about your medical history is essential before using Tadalafil. 

Recommended read: Discover the connection between high blood pressure and ED in our article – Can High Blood Pressure Cause Erectile Dysfunction?

Frequently Asked Questions

Does Tadalafil lower blood pressure?

Tadalafil’s systemic vasodilatory actions can reduce blood pressure. The degree of blood pressure drop differs from person to person, as well as how they react to the medication.

Is Tadalafil used for high blood pressure?

Tadalafil is used to treat Pulmonary Hypertension (high blood pressure in the lungs). It eases blood flow by enlarging arteries and reduces lung blood pressure.

What does Tadalafil do to your heart?

By boosting blood flow, Tadalafil can impact the heart which may aid in easing Pulmonary Arterial Hypertension (PAH) symptoms.
Nitrates shouldn’t be consumed along with the drug. This may cause blood pressure to fall dangerously.

Is Tadalafil safe for heart patients?

Heart patients shouldn’t use Tadalafil. It may interact with heart disease medications like Nitrates and Alpha-blockers. The combination may result in further drop in blood pressure. If you suffer from cardiovascular problems, consult your doctor. 

Can Tadalafil help with Pulmonary Arterial Hypertension?

Yes, Tadalafil is approved for treating Pulmonary Arterial Hypertension (PAH). It relaxes the pulmonary blood lungs, enhances blood flow, and lightens the heart’s stress.

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