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Xinep 5 ml
Xinep 5 ml
Trusted Source-
Treats Post-Operative Eye Inflammation
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FDA-approved active ingredient
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Exclusive offers and competitive pricing
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Quality service- your trust is our goal
Medically Reviewed by Dr. Akansha Kaushal
Written by Julian Carter
What is Xinep 5 ml
Xinep is a nonsteroidal eye drop that includes Nepafenac, an FDA-approved active ingredient that treats Postoperative Eye Inflammation, usually Cataract surgery-related pain, swelling, redness, and irritation. Sunways India Pvt. Ltd. manufactures the product.
0.1% Nepafenac treats all kinds of inflammatory symptoms observed after eye surgeries, including Cataract surgery. It also relieves post-operative pain and benefits the user by alleviating itching, swelling, watering, and redness.
Uses of Xinep 5 ml
NSAID (Nonsteroidal Anti-Inflammatory Drug) ophthalmic solution is widely preferred to deal with Postoperative Eye Inflammation and pain. It reduces redness, swelling, and irritation, which usually follow Cataract surgery.
It also promotes quicker recovery, enhances surgery outcomes, and manages eye discomfort.
The prevention of retina swelling, called Macular Edema, is achieved by the secondary usage of Xinep 5 ml. This medication can be preferred over steroidal ocular medicines to avoid the risk of Glaucoma (optic nerve damage) that is triggered by prolonged steroid use for the eyes.
Working and benefits of Nepafenac
Nepafenac eye drops are an NSAID that effectively penetrates the cornea and quickly becomes functional (bioactive) by converting into its active form, Amfenac. This form, in turn, blocks enzymes responsible for prostaglandin synthesis.
Since Prostaglandins are responsible for inflammatory symptoms, inhibiting enzymes lowers swelling, pain, and other inflammatory responses generated after Cataract surgery.
The following benefits of Nepafenac boost the product’s effectiveness and provide quick relief:
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Nepafenac 0.1% causes less discomfort than Ketorolac 0.5%. (an NSAID). Also, it was found clinically superior to Ketorolac for treating eye inflammation and pain.
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Nepafenac also helps to prevent CME (Cystoid Macular Edema, which is swelling of the retina due to fluid accumulation) post-Cataract surgery.
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Enhances comfort and promotes visual recovery. It also helps in improving surgical results.
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It is a better and safer alternative to steroidal eyedrops as it lowers the risk of eye pressure. This makes the eye drop a preferable option for individuals who are at risk of steroid-induced Glaucoma.
Dosage and how to take Xinep 5 ml
The doctor must adjust the exact duration and dose of the prescription NSAID eye drops. The general dosage guideline is 1 drop 3 times a day for 14 days after Cataract surgery. Medication should begin 24 hours before the surgery.
Directions for taking the eye dose:
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Thoroughly wash your hands before use.
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Pull your lower eyelid down after tilting your head back and instill a prescribed number of drops into your eyes. Avoid touching the dropper tip to the eye.
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Gently close your eyes for 1-2 minutes and then press the inner corner of the eye to promote medication absorption.
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Take a gap of 5-10 minutes to prevent dilution if you apply other eye medications.
Strengths and substitutes
Currently, no strengths or substitutes for Xinep 5ml are available at GoodRxMedicine.
Side effects
Here are the side effects of Xinep 5 ml:
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Itchy, dry, or sticky eyes
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Redness or swelling in the eyes
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Dizziness or headaches (less common)
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Sensitivity to light (rare)
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Blurred vision
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Increased eye pressure
Although rare, if you experience severe side effects like eye discharge or bloody eyes, immediately contact a doctor.
Interactions
Anti-inflammatory eye drops can interact with other medications, health conditions, and food and drink preferences.
Drug interactions
Xinep have significant interactions with medications as follows:
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Steroid eye drops, like Hydrocortisone
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Blood thinners, such as Warfarin or Aspirin
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Other NSAIDs, as the interaction may increase bleeding risk in the user.
However, for safety, keep the doctor informed about all medications, supplements, and herbal products actively being taken to avoid any potential interactions.
Disease interactions
This medication can worsen bleeding disorders or increase the risk of bleeding in the eye, especially after eye surgery. It may also interact with Rheumatoid arthritis and trigger the risk of severe eye complications.
In a study, 3% of the diabetic individuals suffered from Punctate Keratitis (cornea disorder) due to prolonged (more than 2 months) Nepafenac use. This medication may also adversely impact individuals with Hypersensitivity (Acute Rhinitis, Asthma, and Urticaria).
Food interactions
No food and beverage interactions are known. Individuals can take Xinep without any diet restrictions.
Precautions
The following precautions must be considered before taking Xinep 5 ml:
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Avoid usage if you are allergic to NSAIDs or any of the ingredients in Xinep.
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When not in use, keep the bottle tightly closed.
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This medication may increase the risk of developing problems in the front part of the eye (cornea). Be cautious and immediately inform a doctor if you have blurred vision or pain.
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Avoid using this drop during pregnancy, particularly in the third trimester, as it may trigger severe cardiovascular complications in the fetus.
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Many drugs are excreted in human milk, so it is suggested to consult a doctor before consuming Nepafenac during breastfeeding.
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Xinep 5 ml review about efficacy and quality
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Write a review
What are the benefits of Nepafenac eye drop?
Nepafenac benefits the user by treating symptoms after an eye procedure, such as Cataract surgery. Symptoms include swelling, inflammation, and pain. It helps in visual recovery and prevents post-operative complications.
Can Nepadenac increase eye pressure?
No, Nepafenac does not increase intraocular pressure (IOP, that is, eye pressure). In fact, this medication is usually preferred over steroidal eye drops for individuals who are sensitive to steroid-induced increases in IOP.
What is the duration of action of Nepafenac?
When topically administered, Nepafenac's duration of action is more than or equal to 8 hours, while its onset of activity is 15 minutes. It is rapidly bioactivated (chemically altered into a different form to trigger an effect inside the body) to its functional form, Amfenac.
Does Nepafenac cause bleeding?
Yes, Nepafenac may worsen the condition if you are already dealing with a bleeding disorder or are actively on medications that can potentially increase the chances of bleeding. It is better to consult a doctor first.
What is another name for Nepafenac eye drops?
Nepafenac is sold under the brand name Xinep. It is an NSAID (nonsteroidal anti-inflammatory adrug) particularly used to treat inflammation and pain in the eye after Cataract surgery. 5 ml of Xinep contains 0.1% Nepafenac as an active ingredient.
Can Nepafenac cause blurry vision?
Yes, Nepafenac can cause blurry vision, which is one of its temporary side effects. This effect appears shortly after you instill the drops and subsides on its own as the eyes adjust to the dose. It is advised to avoid driving until the vision becomes clear.
Are Nepafenac eye drops a steroid?
No, Nepafenac eye drops are not steroid. They are Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) that function by lowering inflammation and pain in the eyes. Steroidal eye drops also have the same benefit but mode of function is different.
