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Supatret Gel .04% (20 gm)

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What is Supatret

Supatret gel .04 contains Tretinoin, which is a form of vitamin A.

It is used to treat acne, a common skin problem that arises when skin pores become clogged, resulting in blackheads, whiteheads, and pimples, by regulating oil production in the skin.

It also helps to smooth rough facial skin and reduces the appearance of facial wrinkles.

This prescription-based medicine is FDA-approved and can only be purchased with a doctor's recommendation. 

Sun Pharmaceutical is the leading pharmaceutical company that manufactures Supatret gel. 

What is Supatret used for

Supatret gel .04 is prescribed for treating acne and reducing fine lines. 


Acne is a skin disorder when hair follicles become clogged with oil and dead skin cells, resulting in blackheads, whiteheads, and pimples.

It contains Tretinoin, a class of medications called Retinoids. It is intended to prevent and cure acne.

Additionally, it decreases the occurrence of new acne outbreaks and helps the skin renew itself. 

Reduces Wrinkles 

It is also known to reduce the appearance of facial lines and wrinkles.

Tretinoin is the most effective when working within a skin care regimen that includes sunscreen.

However, it does not permanently erase the deep fine lines induced by the sun or age-related deep wrinkles.

How does Supatret work

Tretinoin, the active salt of Supatret Gel, is a form of vitamin A. 

It decreases the skin's oil production and treats bacteria that cause acne and inflammation. It helps replenish acne-prone skin.

To reduce the appearance of wrinkles, it stimulates the production of new collagen and blood vessels in the skin. 

How do you use Supatret

Stick to your doctor's prescription. These quick tips might help you.

  • Before applying this medication, clean the affected skin with a mild or soapless cleanser and pat dry
  • Use your fingertips to apply a pea size medication in a thin layer, usually once daily at bedtime or as your physician directs 
  • After cleaning your skin, wait for 20 to 30 minutes before applying Supatret
  • The topical application of medication is limited to the skin. Do not apply to burnt or Eczema-affected skin
  • Do not wash or apply any skin products to the treated area for at least one hour after applying this gel
  • Avoid contact with the eyes. If Supatret gel enters your eyes, wash them thoroughly. Consult a physician if eye irritation develops
  • After using the medication, wash your hands to avoid accidentally getting it in your eyes

Side effects of Supatret

If you stick to your doctor's prescription, it is very rare to experience adverse effects. However, it may induce some side effects. Contact your doctor if you have

  • Burning, itching, or irritation of the skin
  • Swelling, blistering, flaking, or crusting of the skin
  • Skin dryness
  • Sore throat
  • Changes in the color of treated skin
  • Mild stinging where the medicine is applied

These side effects are temporary. However, if it causes you to worry, consult your doctor.


Interactions differ from person to person. Check all the potential interactions with your doctor to avoid any adverse consequences.

Drug Interaction

Inform your physician about all your medicines, including prescription and non-prescription medicines, vitamins, and herbal products.

  • Skin products containing Benzoyl Peroxide
  • Clascoterone topical
  • Porfimer
  • Aminolevulinic acid 
  • Verteporfin
  • Methoxsalen
  • Salicylic Acid (Topical)
  • Sulphur topical 
  • Isotretinoin
  • Aminolevulinic acid topical
  • Resorcinol topical
  • Methyl Aminolevulinate topical

Disease Interaction

To avoid all the medicine-disease interactions, inform about your medical history to the doctor. 


Sunburn is due to excessive exposure to UV radiation from the sun. It is characterized by red and painful skin. The use of Supatret gel may cause severe irritation if you have sunburn.


Eczema is a skin condition characterized by itchy, swelling, and cracked patches. If you have this condition, you should not use Supatret gel since it may have undesirable side effects.


One must take extensive care when using Supatret gel:

  • If you are allergic to Tretinoin, you should avoid using it. Seek medical attention immediately if you experience symptoms such as a rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, etc
  • Supatret gel is intended for topical use only. Avoid contact with the eyes, nose, and mouth
  • Inform your physician of your medical history, especially of: Eczema, before using this medication
  • This medicine may increase your sun sensitivity. Limit your sun exposure
  • Extreme weather conditions can also irritate the skin
  • Apply sunscreen daily and wear protective clothes. Inform your doctor immediately if you have sunburn or blistering/redness of the skin
  • While using this treatment, avoid electrolysis, waxing, and chemical depilatories for hair removal on the treated regions
  • Supatret may interact with other cosmetics or pharmaceuticals. 
  • Avoid using medicated or abrasive soaps, and cosmetics with a strong drying effect (such as Alpha Hydroxy acids, Glycolic acid)
  • Do not use Sulphur, Resorcinol, or Salicylic acid-containing products


  • Keep Supatret at room temperature and protect it from light and moisture
  • Avoid storing medicines in a bathroom
  • Keep children and pets away from medications
  • When this item has expired or is no longer needed, dispose of it properly

Frequently Asked Questions 

What is Supatret used for?

Supatret gel treats acne, a skin condition that develops when oil and dead skin cells block hair follicles, causing blackheads, whiteheads, and pimples. It also minimizes facial wrinkles.

Can you use Tretinoin under your eyes?

Do not apply this medication to the lips, eyes, or nose. When applying, spread the medication away from these areas. If it accidentally gets on these areas, immediately rinse with water. 

What should you not use with Tretinoin?

Unless advised otherwise by your doctor, you must avoid applying the following skin products. Any other topical acne treatment or skin care product with a peeling agent (e.g., Benzoyl Peroxide, Resorcinol, Salicylic acid, or Sulfur).

Do we need to wash Tretinoin off in the morning?

You must apply Tretinoin at night and wash it off the next morning. For the best advice according to your medical condition, consult your doctor. 

How long should I leave Tretinoin on my face?

After using Tretinoin, you should wait at least one hour before cleaning the affected area. Do not apply topical medication to the affected area within one hour before or after using Tretinoin.

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