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Isentress 400 Mg Tablet
Isentress 400 Mg Tablet
26 orders placed last week
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Antiretroviral medication for HIV treatment
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Contains FDA-approved active ingredient (Raltegravir)
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Starts working within 2 to 4 weeks
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Discreet packaging, as your privacy is our top priority


What is Isentress 400 mg
Isentress 400 mg is an antiretroviral medication manufactured by MSD Pharmaceuticals Ltd. It is used primarily to treat HIV (Human Immunodeficiency Virus) in adults and children. It contains an FDA-approved active ingredient, 400 mg of Raltegravir. The medicine belongs to the drug class of HIV integrase inhibitors.
It is combined with other antiretrovirals to treat HIV-1 infection by preventing viral replication. It helps reduce viral load and manage HIV/AIDS, but it is not a cure for the disease.
Uses of Isentress 400 mg
Isentress 400 mg is effective against HIV infections in the following manner:
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Taken alongside other antiretroviral drugs to treat HIV and reduce the amount of virus in the body.
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When used correctly, it can help lower the chances of spreading HIV to others.
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Occasionally included in Post-Exposure Prophylaxis (PEP) treatments after potential HIV exposure.
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Strengthens the immune system, helping to prevent opportunistic infections.
While the primary use is for HIV-1 infection, it can also be prescribed for other conditions as determined by a healthcare provider, though these are less common and not its primary purpose.
Working and benefits of Raltegravir
Raltegravir, the active ingredient in Isentress, is an HIV-1 Integrase Strand Transfer Inhibitor (INSTI) that targets the integrase enzyme essential for HIV replication. This enzyme helps the virus insert its genetic code into the DNA of human immune cells.
By disrupting this process, Raltegravir stops HIV from integrating into the host DNA, which prevents the virus from multiplying and lowers the overall amount of HIV in the body. Unlike some other HIV drugs, Raltegravir has little effect on normal cell functions, making it highly targeted against HIV.
The main benefits of Raltegravir include:
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It lowers the amount of HIV in the body while boosting immune cell (CD4) counts, which increases immune response and reduces the risk of opportunistic infections.
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Raltegravir poses a lower risk of interacting with other medications, making it suitable for patients on complex treatment regimens.
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It is associated with fewer metabolic side effects, such as changes in blood lipids or insulin sensitivity, which are more common with other HIV drugs.
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Raltegravir is a valuable treatment option for individuals with HIV strains resistant to other medications.
Dosage and how to take Isentress 400 mg
Here are some general guidelines on how to take Isentress 400 mg safely:
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Take the dosage per the doctor's instructions.
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Take it twice a day, with or without food.
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Swallow the whole tablet with water. Do not crush or chew it.
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For better results, take it at a fixed time daily.
Always adhere to the doctor's recommendations to prevent any complications.
Side effects
Some common Isentress 400 mg side effects are:
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Headache
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Fatigue
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Nausea
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Dizziness
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Diarrhea
They are temporary and will not require medical attention. However, if the effects continue or worsen, contact your doctor for further assistance.
Interactions
Isentress 400 mg tablet may interact with certain drugs, foods, or existing health conditions like many medications.
Drug interactions
Consider the following drug interactions while taking the medicine:
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Antacids
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Rifampin
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H2 Blockers like Ranitidine
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Warfarin
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Other HIV medicines
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Metformin
It is not an exhaustive list. Please consult your healthcare professional and discuss any possible interactions with your medications.
Disease Interactions
People having the following underlying conditions should be cautious while taking Isentress 400 mg:
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Diabetes: Isentress might slightly affect blood sugar levels, so individuals with Diabetes should be closely monitored.
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Liver disease: Use Isentress cautiously in people with moderate to severe liver problems, as the drug is processed by the liver.
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Phenylketonuria (PKU): Certain versions of the medication contain phenylalanine, which can have severe effects on people with PKU.
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Myopathy: There's a higher risk of muscle pain, weakness, or muscle breakdown, especially when combined with statins or other drugs that affect muscles.
Food Interactions
While no major food interactions have been noted, a few factors should be kept in mind:
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High-fat meals may slightly increase Raltegravir levels, but dose adjustments might not be necessary.
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Polyvalent cations can be found in antacids, dairy products, and supplements; these can reduce Raltegravir absorption. Caution is advised.
Precautions
Patients should take the following precautions before and while taking this antiretroviral therapy pill:
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Do not take the medication if you are allergic to Raltegravir.
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Isentress 400 mg helps manage HIV is not a cure for it. Always take precautions to avoid HIV transmission.
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Monitor your blood sugar levels frequently, as some HIV medications may impair glucose metabolism.
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Do not share the medication with others; take it exactly as prescribed.
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Consult a physician as soon as possible if you contract severe skin reactions, muscular pain, swelling, or difficulty breathing.
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Isentress 400 mg is contraindicated during pregnancy.
Why buy from us
When you buy Isentress online from GoodRxMedicine, you enjoy advantages such as:
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Genuine product
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24*7 Customer support
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Reliable quality
Is Isentress safe during breastfeeding?
No, Isentress 400 mg is not recommended during breastfeeding for women living with HIV. It is primarily to avoid the risk of postnatal HIV transmission to the infant, as current guidelines advise HIV-infected mothers not to breastfeed.
Can I drive or operate machinery while taking Isentress 400 mg?
You should avoid driving or operating machinery while taking Isentress 400 mg if you experience side effects such as dizziness, drowsiness, or vision changes, which may decrease alertness and impair your ability to drive or handle equipment safely.
Can I take Isentress with other medications?
Yes, you can take Isentress with other medications. However, certain drugs can negatively interact with it. You must inform your doctor about the medicines before starting Isentress to prevent complications.
What should I do if I miss a dose of Isentress 400 mg?
If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed one and stick to your usual dosing schedule. Do not take two doses simultaneously to make up for the missed dose.
Is Isentress enough for PEP (Post-Exposure-Prophylaxis)?
Isentress is an essential part of PEP but must be combined with other antiretroviral medications. It is not enough to use Isentress alone. Always follow your healthcare provider's instructions for the correct regimen.