Augmentin 1000 Mg

Medically Reviewed by Dr. Akansha Kaushal

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Dr. Akansha Kaushal

Clinical Pharmacologist and Drug Safety Expert

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Written by Julian Carter

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Julian Carter

MBA in Pharmaceutical Management

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What is Augmentin 1000 mg

Augmentin 1000 mg is a broad-spectrum antibiotic used to treat bacterial infections. It contains two FDA-approved active ingredients: Amoxicillin and Clavulanic Acid, a combination serving as a powerful antibiotic. The medication belongs to the penicillin class of antibiotics, specifically classified as a beta-lactam/beta-lactamase inhibitor combination. GlaxoSmithKline Pharmaceuticals Ltd manufactures the product. 

This medication primarily treats moderate to severe bacterial infections, such as respiratory tract, skin, and urinary tract infections, providing broad-spectrum coverage under medical supervision.

Uses of Augmentin 1000 Mg

Augmentin 1000 mg effectively helps the body fight infections caused by bacteria such as:

• Respiratory tract infections (e.g., Pneumonia, Bronchitis)

• Urinary tract infections (UTIs) 

• Skin and soft tissue infections, like wound infections

Secondary uses include treating infections of the bones, joints, and intra-abdominal areas, certain bite wounds, and Odontogenic (tooth-related) infections. It is also indicated for acute exacerbations of chronic obstructive pulmonary disease and mild to moderate intra-abdominal infections in specific patient groups.

Working and benefits of Amoxicillin and Clavulanic Acid

Augmentin 1000 mg contains two active ingredients: 875 mg of Amoxicillin and 125 mg of Clavulanic Acid. Amoxicillin is a penicillin-type antibiotic that kills bacteria by blocking the formation of their cell walls, causing them to break apart and die. However, some bacteria can resist Amoxicillin by producing enzymes called Beta-Lactamases that destroy it. Clavulanic acid helps by blocking these enzymes, protecting Amoxicillin and allowing it to work against a broader range of bacteria. Together, they make Augmentin a strong and effective antibiotic.

Key benefits include:

• Provides broad-spectrum protection against a wide variety of bacterial strains.

• Especially effective for infections that don’t respond well to other antibiotics.

• Begins to work within hours, quickly reducing bacterial load and symptoms.

• Has a high success rate and is generally well-tolerated by most patients.

• Its formulation is designed to treat persistent and recurring infections effectively.

• Widely trusted by doctors and patients for its reliability and effectiveness.

Dosage and how to take Augmentin 1000 mg

Here's how to take Augmentin 1000 Mg dosage safely and effectively:

• Take the medication per the doctor’s instructions.

• Swallow the whole tablet with water. Do not crush or chew it. 

• It should be taken with food.

• Take it at a fixed time daily for better results.

Always follow your doctor's instructions for practical usage and results while taking Augmentin. 

Side effects

Though well-tolerated, this medication may also cause some side effects:

• Nausea

• Vomiting

• Skin rash

• Itching

• Vaginal inflammation

• Diarhea

Augmentin 1000 mg side effects will subside as the body adjusts to the medication and will not require medical attention. However, consult a doctor if the symptoms continue or worsen.

Interactions

Augmentin may interact with other medications you take, your health conditions, or specific foods or drinks.

Drug interactions

Medicines that can interact negatively with Augmentin 1000 mg are:

• Oral Anticoagulants (blood thinners)

• Probenecid

• Allopurinol

• Methotrexete

• Oral Contraceptive pills

It is not a comprehensive list. Please consult your healthcare provider to determine any possible interactions with Augmentin.

Disease interactions

Patients with the following conditions should be cautious while taking the medication.

• Liver Disease: Patients with pre-existing liver conditions should use Augmentin cautiously; regular liver function monitoring is advised.

• Kidney Impairment: Augmentin is not recommended for those with severe kidney disease unless under close medical supervision.

• Mononucleosis: Use of Augmentin in patients with Mononucleosis increases the risk of developing a severe skin rash.

• Colitis: Augmentin may exacerbate or cause colitis (inflammation of the colon), especially if there is a history of gastrointestinal disease.

• Diabetes: Caution is needed as Augmentin may affect glucose control or require monitoring in diabetic patients.

• Phenylketonuria (PKU): The liquid form of Augmentin contains phenylalanine, which can be harmful to people with PKU. Tablets are preferred for these patients.

Always inform your healthcare provider about your medical history before starting Augmentin.

Food interactions

There are no known food interactions with Augmentin 1000 mg. However, it is recommended that you consult a doctor before making any dietary changes. 

Precautions

Patients should take the following precautions before and while using the Augmentin tablet 1000 mg: 

• Do not use this medication if you are allergic to Amoxicillin or Clavulanic Acid.

• Pregnant women can take Augmentin 1000 mg, but only if prescribed by a doctor.

• Although generally safe during breastfeeding, nursing mothers should consult their doctor before use.

• Individuals with liver or kidney conditions should use this medicine under medical supervision to minimize health risks.

• Avoid alcohol during treatment, as it may worsen side effects such as nausea and dizziness.

•  People with a history of colitis or other digestive disorders should use it with caution to prevent severe diarrhea.

• Let your doctor know about any other medications you're taking to help avoid harmful drug interactions.

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