Crestor 40 Mg

Medically Reviewed by Dr. Akansha Kaushal

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Dr. Akansha Kaushal

Clinical Pharmacologist and Drug Safety Expert

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Written by Julian Carter

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Julian Carter

MBA in Pharmaceutical Management

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What is Crestor 40 mg

Crestor 40 mg, manufactured by AstraZeneca, is a film-coated tablet containing Rosuvastatin of the strength 40 mg as its active ingredient. It belongs to the drug class of HMG-CoA Reductase Inhibitors (statins). 

Crestor is used to decrease bad cholesterol (LDL) and triglycerides, simultaneously increasing good cholesterol (HDL) and lowering the chance of cardiovascular events in adults and children with specific inherited conditions, alongside diet and lifestyle changes.

Uses of Crestor 40 mg

Crestor 40 mg is primarily used for the following:

• Reduces bad cholesterol and triglycerides

• Increases good cholesterol

• Prevents heart disease

• Prevents stroke

Other uses include helping slow the advancement of Atherosclerosis (plaque buildup in the arteries) and managing inherited cholesterol conditions like Heterozygous and Homozygous Familial Hypercholesterolemia in suitable patients. It's also prescribed to lower the risk of cardiovascular events in adults with specific risk factors.

Working and benefits of Rosuvastatin

Rosuvastatin, the main component of Crestor 40 mg, belongs to the statin family (HMG-CoA reductase inhibitors). It reduces cholesterol in two ways: by inhibiting the HMG-CoA reductase enzyme in the liver to limit cholesterol production and by improving the liver's ability to absorb and eliminate cholesterol from the bloodstream.

As the liver produces less cholesterol, it increases the number of LDL receptors on its surface, which helps clear more bad cholesterol from the blood. Additionally, Rosuvastatin lowers very low-density lipoprotein levels, which reduces triglycerides and raises good cholesterol, helping remove excess cholesterol from the body.

Key benefits of Crestor 40 mg include:

• It effectively reduces LDL and triglycerides while increasing HDL cholesterol.

• It provides strong results even at lower doses compared to other statins.

• It enhances blood vessel function and reduces inflammation beyond just lowering lipids.

• It helps prevent heart attacks, strokes, and the progression of Atherosclerosis.

Dosage and how to take Crestor 40 mg

Here are some general guidelines on how to take the Crestor 40 mg dosage safely and effectively:

• Take the dosage per the doctor's instructions.

• Take it once a day, with or without food.

• Swallow the whole tablet with water. Do not crush or chew it. 

• For better results, take it at a fixed time daily.

Always adhere to the doctor's recommendations to prevent any complications.

Side effects

Side effects of Crestor 40 mg are: 

• Muscle pain

• Headache

• Abdominal pain

• Weakness

• Nausea

Fortunately, most Crestor side effects are temporary and mild. However, if these effects continue or worsen, consult a doctor as soon as possible.

Interactions

Crestor may interact with certain drugs, foods, or existing health conditions, like many medications.

Drug Interactions

Medicines that can interact with 40 mg of Crestor are:

• Antiviral medications (including HIV and Hepatitis viral medications)

• Darulotamide

• Regorafenib

• Gemfibrozil 

• Cyclosporine

• Warfarin

It is not an exhaustive list. Consult your doctor and discuss any possible interactions with your medications.

Disease interactions

Patients with a history of the following should be cautious while taking the medication.

• Liver Disease: It is not advised for individuals with acute liver failure or advanced Cirrhosis to use Crestor 40 mg, as it can further impair liver function.

• Diabetes: Crestor can cause a slight rise in blood sugar, so regular monitoring is advised for diabetic patients.

• Muscle Disorders: People with a history of muscle conditions such as myopathy or rhabdomyolysis are more likely to experience severe muscle complications.

• Cognitive Issues: Although uncommon, some statin users, especially those with existing cognitive conditions, have reported memory lapses and confusion.

Always inform your healthcare provider about your underlying conditions to prevent severe complications.

Food interactions

There are no known food interactions with the Crestor 40 mg tablet that can have adverse effects. However, it is essential to avoid alcohol consumption as it may increase the risk of liver damage. 

Precautions

Patients should take the following precautions while or before taking the LDL cholesterol reducer:

• Do not take Crestor 40 mg if allergic to Rosuvastatin or its components.

• Always consult your healthcare provider before stopping or adjusting the dosage.

• Follow a heart-healthy diet and stay active to support your treatment.

• Tell your doctor about all other medications you use to prevent adverse interactions.

• Crestor should not be used during pregnancy or while breastfeeding.

Why buy from us

When you purchase Crestor online from GoodRxMedicine, you benefit from:

• Special discounts and affordable rates

• Secure and private packaging

• Quick and dependable shipping

• Dedicated customer support is available to help with any queries or issues